製品の概要

  • 製品名Anti-EFTUD2 antibody
    EFTUD2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EFTUD2
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide derived from internal region of human EFTUD2.

  • ポジティブ・コントロール
    • HUVEC and 293 cells

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab92479 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
IHC-P
  • 追加情報ELISA: 1/40,000.
    IHC-P: 1/50 - 1/100.
    WB: 1/500 - 1/1000. Predicted molecular weight: 109 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Component of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP.
    • 関連疾患Defects in EFTUD2 are the cause of mandibulofacial dysostosis with microcephaly (MFDM) [MIM:610536]. A rare syndrome characterized by progressive microcephaly, midface and malar hypoplasia, micrognathia, microtia, dysplastic ears, preauricular skin tags, significant developmental delay, and speech delay. Many patients have major sequelae, including choanal atresia that results in respiratory difficulties, conductive hearing loss, and cleft palate.
    • 配列類似性Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
    • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 116 kDa antibody
      • 116 kDa U5 small nuclear ribonucleoprotein component antibody
      • EFTUD2 antibody
      • Elongation factor Tu GTP binding domain containing 2 antibody
      • Elongation factor Tu GTP-binding domain-containing protein 2 antibody
      • hSNU114 antibody
      • MFDGA antibody
      • MFDM antibody
      • SNRNP116 antibody
      • Snrp116 antibody
      • Snu114 antibody
      • SNU114 homolog antibody
      • U5 116KD antibody
      • U5 small nuclear ribonucleoprotein component antibody
      • U5 snRNP specific protein, 116 kD antibody
      • U5 snRNP specific protein, 116 kDa antibody
      • U5 snRNP-specific protein antibody
      • U5-116 kDa antibody
      • U5-116KD antibody
      • U5S1_HUMAN antibody
      see all

    Anti-EFTUD2 antibody 画像

    • All lanes : Anti-EFTUD2 antibody (ab92479) at 1/500 dilution

      Lane 1 : HUVEC cells (-peptide)
      Lane 2 : 293 cells (-peptide)
      Lane 3 : HUVEC cells (+peptide)

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 109 kDa
    • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using ab92479 A) - peptide B) + peptide

    Anti-EFTUD2 antibody (ab92479) 使用論文

    ab92479 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab92479.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"