製品の概要

  • 製品名Anti-EFHC1 antibody
    EFHC1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EFHC1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-640 of Human EFHC1 (AAH20210.1).

  • ポジティブ・コントロール
    • Mouse testis; EFHC1 transfected 293T cell line lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab103824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 74 kDa.

ターゲット情報

  • 機能Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration (PubMed:22926142). May enhance calcium influx through CACNA1E and stimulate programmed cell death (PubMed:15258581).
  • 組織特異性Widely expressed. Not detected in lymphocytes.
  • 関連疾患Juvenile myoclonic epilepsy 1
    Juvenile absence epilepsy 1
    Mutation Leu-229 may be a cause of intractable epilepsy of infancy. Affected individuals have seizures of multiple type, manifested as tonic, clonic, and myoclonic seizures in the neonatal period, and as tonic seizures activated frequently by sleep, and repeated frequent myoclonic seizures in later infancy. The seizures are unresponsive to numerous antiepileptic drugs, and infants die in the first years of life. Although heterozygosity for Leu-229 has been associated with relatively benign forms of epilepsy in adolescence, homozygosity for the same mutation has much more severe consequences.
  • 配列類似性Contains 3 DM10 domains.
    Contains 1 EF-hand domain.
  • 細胞内局在Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EF hand domain (C terminal) containing 1 antibody
    • EF hand domain containing protein 1 antibody
    • EF-hand domain-containing protein 1 antibody
    • Efhc1 antibody
    • EFHC1_HUMAN antibody
    • EJA1 antibody
    • EJM1 antibody
    • FLJ10466 antibody
    • FLJ37290 antibody
    • JAE antibody
    • Myoclonin 1 antibody
    • Myoclonin-1 antibody
    see all

Anti-EFHC1 antibody 画像

  • Anti-EFHC1 antibody (ab103824) at 5 µg/ml + Mouse testis tissue lysate at 50 µg

    Predicted band size : 74 kDa
  • All lanes : Anti-EFHC1 antibody (ab103824) at 5 µg/ml

    Lane 1 : EFHC1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 74 kDa

Anti-EFHC1 antibody (ab103824) 使用論文

ab103824 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab103824.
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