製品の概要

  • 製品名Anti-EFCAB4B antibody
    EFCAB4B 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EFCAB4B
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Guinea pig, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 71-120 (ARKDMQRLHK ELPLSLEELE DVFDALDADG NGYLTPQEFT TGFSHFFFSQ) of Human EFCAB4B (NP_116069)

  • ポジティブ・コントロール
    • NCI-H226 cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab98039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Ca(2+)-binding protein that plays a key role in store-operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.
  • 配列類似性Belongs to the EFCAB4 family.
    Contains 2 EF-hand domains.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Calcium release-activated calcium channel regulator 2A antibody
    • CRAC channel regulator 2A antibody
    • CRACR2A antibody
    • EF hand calcium binding domain 4B antibody
    • EF hand calcium binding domain containing protein 4B antibody
    • EF-hand calcium-binding domain-containing protein 4B antibody
    • EFC4B_HUMAN antibody
    • EFCAB 4B antibody
    • Efcab4b antibody
    • FLJ33805 antibody
    • MGC4266 antibody
    see all

Anti-EFCAB4B antibody 画像

  • Anti-EFCAB4B antibody (ab98039) at 1 µg/ml + NCI-H226 Cell Lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 50000

    Predicted band size : 46 kDa

Anti-EFCAB4B antibody (ab98039) 使用論文

ab98039 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"