Anti-EDIL3/DEL1 抗体 [4C9] (ab88667)
Key features and details
- Mouse monoclonal [4C9] to EDIL3/DEL1
- Suitable for: WB
- Reacts with: Human, Recombinant fragment
- Isotype: IgG2a
製品の概要
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製品名
Anti-EDIL3/DEL1 antibody [4C9]
EDIL3/DEL1 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [4C9] to EDIL3/DEL1 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human, Recombinant fragment
交差が予測される動物種: Mouse, Xenopus laevis, Zebrafish, Orangutan -
免疫原
Recombinant fragment corresponding to Human EDIL3/DEL1 aa 100-200.
Database link: O43854 -
ポジティブ・コントロール
- Partial tagged recombinant Human EDIL3/DEL1 protein (the immunogen). Human pancreas tissue lysate.
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特記事項
This product was changed from ascites to tissue culture supernatant on 30th April 2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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精製度
Tissue culture supernatant -
特記事項(精製)
Purified from TCS. -
ポリ/モノ
モノクローナル -
クローン名
4C9 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab88667の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (2) |
Use at an assay dependent concentration. Predicted molecular weight: 54 kDa.
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特記事項 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 54 kDa. |
ターゲット情報
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機能
Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development. -
配列類似性
Contains 3 EGF-like domains.
Contains 2 F5/8 type C domains. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 10085 Human
- Entrez Gene: 13612 Mouse
- Entrez Gene: 100173296 Orangutan
- Entrez Gene: 403365 Xenopus laevis
- Omim: 606018 Human
- SwissProt: O43854 Human
- SwissProt: O35474 Mouse
- SwissProt: Q5R7K9 Orangutan
see all -
別名
- DEL1 antibody
- Developmental endothelial locus 1 antibody
- Developmentally regulated endothelial cell locus 1 protein antibody
see all
画像
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Anti-EDIL3/DEL1 antibody [4C9] (ab88667) at 5 µg/ml + Partial tagged recombinant human EDIL3/DEL1 protein (the immunogen) at 0.2 µg
Predicted band size: 54 kDa
Observed band size: 37 kDa why is the actual band size different from the predicted?Western blot against tagged recombinant protein immunogen. Predicted band size of immunogen is 37 kDa.
This image was generated using the ascites version of the product.
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Anti-EDIL3/DEL1 antibody [4C9] (ab88667) at 5 µg/ml + human pancreas tissue lysate at 50 µg
Predicted band size: 54 kDa
Observed band size: 54 kDaThis image was generated using the ascites version of the product.
データシートおよび資料
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Datasheet download
参考文献 (4)
ab88667 は 4 報の論文で使用されています。
- He N et al. Nano pom-poms prepared exosomes enable highly specific cancer biomarker detection. Commun Biol 5:660 (2022). PubMed: 35787656
- Chung JW et al. Identification of a novel non-invasive biological marker to overcome the shortcomings of PSA in diagnosis and risk stratification for prostate cancer: Initial prospective study of developmental endothelial locus-1 protein. PLoS One 16:e0250254 (2021). PubMed: 33901217
- Im EJ et al. Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A. Nat Commun 10:1387 (2019). PubMed: 30918259
- Moon PG et al. Identification of Developmental Endothelial Locus-1 on Circulating Extracellular Vesicles as a Novel Biomarker for Early Breast Cancer Detection. Clin Cancer Res 22:1757-66 (2016). PubMed: 26603257