製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to EDG3
  • アプリケーション
    適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to amino acids within Human EDG3.

  • ポジティブ・コントロール
    • Human Kidney tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115463 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1 - 1/1000.
IHC-P Use a concentration of 10 - 20 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
  • 組織特異性
    Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.
  • 配列類似性
    Belongs to the G-protein coupled receptor 1 family.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EDG 3 antibody
    • EDG3 antibody
    • Endothelial differentiation G protein coupled receptor 3 antibody
    • Endothelial differentiation G-protein coupled receptor 3 antibody
    • Endothelial differentiation gene 3 antibody
    • Endothelial differentiation sphingolipid G protein coupled receptor 3 antibody
    • FLJ37523 antibody
    • FLJ93220 antibody
    • G protein coupled receptor endothelial differentiation gene 3 antibody
    • LPB 3 antibody
    • LPB3 antibody
    • MGC71696 antibody
    • OTTHUMP00000215691 antibody
    • S1P receptor 3 antibody
    • S1P receptor Edg 3 antibody
    • S1P receptor Edg-3 antibody
    • S1P receptor EDG3 antibody
    • S1P3 antibody
    • S1pr3 antibody
    • S1PR3_HUMAN antibody
    • Sphingosine 1 phosphate receptor 3 antibody
    • Sphingosine 1 phosphate receptor Edg 3 antibody
    • Sphingosine 1 phosphate receptor Edg3 antibody
    • Sphingosine 1-phosphate receptor 3 antibody
    • Sphingosine 1-phosphate receptor Edg-3 antibody
    see all

画像

  • ab115463 at 10 µg/ml staining EDG3 in Formalin-fixed, Paraffin-embedded Human kidney tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

プロトコール

参考文献

ab115463 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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