Anti-EDG1 (phospho T236) 抗体 (ab111571)

製品の概要

  • 製品名Anti-EDG1 (phospho T236) antibody
    EDG1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to EDG1 (phospho T236)
  • 特異性ab111571 detects endogenous levels of EDG1 only when phosphorylated at threonine 236 (Human: Thr236; Mouse: Thr236; Rat: Thr237).
  • アプリケーション適用あり: ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic phosphopeptide derived from Human EDG1 around the phosphorylation site of Threonine 236 (R-L-TP-F-R).

  • ポジティブ・コントロール
    • COS-7 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/100 - 1/500.

ターゲット情報

  • 機能Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins.
  • 組織特異性Endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin.
  • 配列類似性Belongs to the G-protein coupled receptor 1 family.
  • 翻訳後修飾S1P-induced endothelial cell migration requires the PKB/AKT1-mediated phosphorylation of the third intracellular loop at the Thr-236 residue.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD363 antibody
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    • D1S3362 antibody
    • ECGF 1 antibody
    • ECGF1 antibody
    • EDG 1 antibody
    • EDG1 antibody
    • endothelial differentiation G protein coupled receptor 1 antibody
    • Endothelial differentiation G-protein coupled receptor 1 antibody
    • Endothelial differentiation sphingolipid G protein coupled receptor 1 antibody
    • FLJ58121 antibody
    • G protein coupled sphingolipid receptor antibody
    • g protein-coupled receptor edg-1 antibody
    • S1P receptor 1 antibody
    • S1P receptor Edg 1 antibody
    • S1P receptor Edg-1 antibody
    • S1P receptor Edg1 antibody
    • S1P(1) receptor antibody
    • S1P1 antibody
    • s1pr1 antibody
    • S1PR1_HUMAN antibody
    • sphingolipid g-protein-coupled receptor 1 antibody
    • Sphingosine 1 phosphate receptor Edg 1 antibody
    • Sphingosine 1 phosphate receptor EDG1 antibody
    • sphingosine 1- phosphate receptor 1 antibody
    • Sphingosine 1-phosphate receptor 1 antibody
    • Sphingosine 1-phosphate receptor Edg-1 antibody
    • Sphingosine 1phosphate receptor type 1 S1P1 antibody
    see all

Anti-EDG1 (phospho T236) antibody 画像

  • ab111571, at 1/100 dilution, staining EDG1 in COS-7 cells by Immunofluorescence, in the presence (right panel) or absence (left panel) of immunising peptide.

Anti-EDG1 (phospho T236) antibody (ab111571) 使用論文

ab111571 has not yet been referenced specifically in any publications.

Product Wall

Application Immunocytochemistry/ Immunofluorescence
Blocking step BSA as blocking agent for 40 minute(s) · Concentration: 1% · Temperature: 21°C
Sample Human Cell (HEK293 overexpressing GFP tagged EDG1)
Specification HEK293 overexpressing GFP tagged EDG1
Permeabilization Yes - 0.1% triton X100 in PBS
Fixative Paraformaldehyde
Username

Mr. Martin Baker

Verified customer

投稿 Nov 10 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"