製品の概要

  • 製品名
    Edaravone (MCI-186)
  • 製品の詳細
    Free radical scavenger with neuroprotective effects
  • 別名
    • MCI-186
  • 生理活性の詳細
    Free radical scavenger and potent antioxidant. Inhibits production of reactive oxygen species, apoptosis and the lipoxygenase system.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Liu N  et al. In vivo optical imaging for evaluating the efficacy of edaravone after transient cerebral ischemia in mice. Brain Res 1397:66-75 (2011). Read more (PubMed: 21571257) »
  • Aoyama T  et al. Edaravone (MCI-186) scavenges reactive oxygen species and ameliorates tissue damage in the murine spinal cord injury model. Neurol Med Chir (Tokyo) 48:539-45; discussion 545 (2008). Read more (PubMed: 19106491) »
  • Kawasaki T  et al. Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum. J Pharmacol Exp Ther 322:274-81 (2007). Read more (PubMed: 17429058) »

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