Anti-EBI3 抗体 (ab72102)

製品の概要

• 製品名Anti-EBI3 antibody
  EBI3 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to EBI3
• アプリケーション適用あり: WBmore details
• 種交差性
  交差種: Human, Chimpanzee
  交差が予測される動物種: Monkey
• 免疫原

  A portion of amino acids 120-170 of Human EBI3

• ポジティブ･コントロール
  • Jurkat cell lysate

製品の特性

• 製品の状態Liquid
• 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• バッファーPreservative: 0.05% Sodium Azide
  Constituents: 0.05% BSA, PBS
• Concentration information loading...
• 精製度Protein G purified
• ポリ/モノポリクローナル
• アイソタイプIgG
• 研究分野
  • Immunology
  • Innate Immunity
  • Cytokines
  • Interleukins

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
• 配列類似性Belongs to the type I cytokine receptor family. Type 3 subfamily.
  Contains 2 fibronectin type-III domains.
• 細胞内局在Secreted.

• Target information above from: UniProt accession Q14213 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 10148 Human
  • Omim: 605816 Human
  • SwissProt: Q14213 Human
  • Unigene: 501452 Human
• 別名
  • cytokine receptor antibody
  • EBI3 antibody
  • EBV induced gene 3 protein antibody

  • EBV-induced gene 3 protein antibody
  • Epstein Barr virus induced 3 antibody
  • Epstein Barr virus induced gene 3 antibody
  • Epstein Barr virus induced gene 3 protein antibody
  • Epstein-Barr virus-induced gene 3 protein antibody
  • IL 27 subunit beta antibody
  • IL 27B antibody
  • IL-27 subunit beta antibody
  • IL-27B antibody
  • IL27 subunit antibody
  • IL27 subunit beta antibody
  • IL27B antibody
  • IL27B_HUMAN antibody
  • IL35 subunit antibody
  • interleukin 27 subunit beta antibody
  • Interleukin-27 subunit beta antibody

  see all