製品の概要
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製品名Anti-EBI3 antibody
EBI3 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to EBI3
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アプリケーション適用あり: WBmore details
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種交差性交差種: Human, Chimpanzee
交差が予測される動物種: Monkey
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免疫原
A portion of amino acids 120-170 of Human EBI3
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ポジティブ･コントロール
- Jurkat cell lysate
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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バッファーPreservative: 0.05% Sodium Azide
Constituents: 0.05% BSA, PBS -
Concentration information loading... -
精製度Protein G purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab72102 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 25 kDa). |
ターゲット情報
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機能Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
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配列類似性Belongs to the type I cytokine receptor family. Type 3 subfamily.
Contains 2 fibronectin type-III domains. -
細胞内局在Secreted.
- Information by UniProt
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参照データベース
- Entrez Gene: 10148 Human
- Omim: 605816 Human
- SwissProt: Q14213 Human
- Unigene: 501452 Human
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別名
- cytokine receptor antibody
- EBI3 antibody
- EBV induced gene 3 protein antibody
see all
Anti-EBI3 antibody 画像
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Western blot - EBI3 antibody (ab72102)All lanes : Anti-EBI3 antibody (ab72102) at 2 µg/ml
Lane 1 : Jurkat cell lysate
Lane 2 : Jurkat cell lysate with immunizing peptide
Predicted band size : 25 kDa
Observed band size : 35 kDa (why is the actual band size different from the predicted?)
Additional bands at : 66 kDa. We are unsure as to the identity of these extra bands.
プロトコール
Anti-EBI3 antibody (ab72102) 使用論文
ab72102 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"