Anti-E3 ubiquitin-protein ligase MUL1 抗体 (ab99096)


  • 製品名Anti-E3 ubiquitin-protein ligase MUL1 antibody
    E3 ubiquitin-protein ligase MUL1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to E3 ubiquitin-protein ligase MUL1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide, corresponding to a region within internal amino acids 143-192 (KPLDSVDLGL ETVYEKFHPS IQSFTDVIGH YISGERPKGI QETEEMLKVG) of Human E3 ubiquitin-protein ligase MUL1 (NP_078820).

  • ポジティブ・コントロール
    • THP1 cell lysate



Our Abpromise guarantee covers the use of ab99096 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • 機能Exhibits weak E3 ubiquitin-protein ligase activity, but preferentially acts as a SUMO E3 ligase at physiological concentrations. Plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
  • 組織特異性Widely expressed with highest levels in the heart, skeletal muscle, placenta, kidney and liver. Barely detectable in colon and thymus.
  • パスウェイProtein modification; protein ubiquitination.
    Protein modification; protein sumoylation.
  • 配列類似性Contains 1 RING-type zinc finger.
  • ドメインThe zinc finger domain is required for E3 ligase activity.
  • 細胞内局在Mitochondrion outer membrane. Peroxisome. Transported in mitochondrion-derived vesicles from the mitochondrion to the peroxisome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 0610009K11Rik antibody
    • AV000801 antibody
    • C1orf166 antibody
    • Chromosome 1 open reading frame 166 antibody
    • E3 SUMO-protein ligase MUL1 antibody
    • E3 ubiquitin ligase antibody
    • E3 ubiquitin protein ligase MUL1 antibody
    • E3 ubiquitin-protein ligase MUL1 antibody
    • FLJ12875 antibody
    • GIDE antibody
    • Growth inhibition and death E3 ligase antibody
    • MAPL antibody
    • Mitochondrial anchored protein ligase antibody
    • mitochondrial E3 ubiquitin ligase 1 antibody
    • mitochondrial E3 ubiquitin protein ligase 1 antibody
    • Mitochondrial ubiquitin ligase activator of NFKB 1 antibody
    • Mitochondrial-anchored protein ligase antibody
    • MUL1 antibody
    • MUL1_HUMAN antibody
    • MULAN antibody
    • Putative NF kappa B activating protein 266 antibody
    • Putative NF-kappa-B-activating protein 266 antibody
    • RGD1309944 antibody
    • RING finger protein 218 antibody
    • RNF218 antibody
    • RP11-401M16.2 antibody
    • RP23-25C1.10-002 antibody
    see all

Anti-E3 ubiquitin-protein ligase MUL1 antibody 画像

  • Anti-E3 ubiquitin-protein ligase MUL1 antibody (ab99096) at 1 µg/ml + THP1 cell lysate at 1 µg

    Predicted band size : 40 kDa

Anti-E3 ubiquitin-protein ligase MUL1 antibody (ab99096) 使用論文

ab99096 has not yet been referenced specifically in any publications.

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