Anti-E2F7 抗体 (ab106832)

製品の概要

• 製品名Anti-E2F7 antibody
  E2F7 一次抗体 製品一覧
• 製品の詳細
  Goat polyclonal to E2F7
• アプリケーション適用あり: WBmore details
• 種交差性
  交差種: Human
  交差が予測される動物種: Cow, Dog, Pig
• 免疫原

  Synthetic peptide:

  C-DLSKQKKFTPERNP

  , corresponding to amino acids 53-66 of Human E2F7 (NP_976328.2).
  Run BLAST with Run BLAST with
• ポジティブ･コントロール
  • Human kidney, testis, heart and brain cerebellum lysates

製品の特性

• 製品の状態Liquid
• 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• バッファーPreservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
• Concentration information loading...
• 精製度Immunogen affinity purified
• 特記事項（精製）Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• ポリ/モノポリクローナル
• アイソタイプIgG
• 研究分野
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Other factors

関連製品

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

アプリケーション

ターゲット情報

• 機能Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription (By similarity). Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
• 配列類似性Belongs to the E2F/DP family.
• ドメインBoth DNA-binding domains are required for DNA-binding and are proposed to form an intramolecular structure that is similar to the winged helix structure of the E2F-DP heterodimer.
• 細胞内局在Nucleus.

• Target information above from: UniProt accession Q96AV8 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 144455 Human
  • Omim: 612046 Human
  • SwissProt: E1BE02 Cow
  • SwissProt: Q96AV8 Human
  • Unigene: 416375 Human
• 製品の状態There are 2 isoforms produced by alternative splicing.
• 別名
  • E2F 7 antibody
  • E2F transcription factor 7 antibody
  • E2F-7 antibody

  • E2f7 antibody
  • E2F7_HUMAN antibody
  • FLJ12981 antibody
  • Transcription factor E2F7 antibody

  see all