Anti-E2F5 抗体 (ab44996)
Key features and details
- Rabbit polyclonal to E2F5
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
製品の概要
-
製品名
Anti-E2F5 antibody
E2F5 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to E2F5 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human E2F5 aa 1-50 (N terminal). 50 amino acid range mapping within amino acids 1-50 ESF-5
-
ポジティブ・コントロール
- MCF7, NIH/3T3 cells.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 0.01% PBS -
Concentration information loading...
-
精製度
Protein G purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab44996の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use at an assay dependent concentration.
|
特記事項 |
---|
WB
Use at an assay dependent concentration. |
ターゲット情報
-
機能
Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. -
配列類似性
Belongs to the E2F/DP family. -
細胞内局在
Nucleus. - Information by UniProt
-
参照データベース
- Entrez Gene: 1875 Human
- Entrez Gene: 13559 Mouse
- Entrez Gene: 116651 Rat
- Omim: 600967 Human
- SwissProt: Q15329 Human
- SwissProt: Q61502 Mouse
- SwissProt: Q62814 Rat
- Unigene: 445758 Human
see all -
別名
- E2F 5 antibody
- E2F transcription factor 5 antibody
- E2F transcription factor 5 p130 binding antibody
see all
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (3)
ab44996 は 3 報の論文で使用されています。
- Sun F et al. MicroRNA-544 inhibits esophageal squamous cell carcinoma cell proliferation and enhances sensitivity to cisplatin by repressing E2F transcription factor 5. Oncol Lett 18:4203-4209 (2019). PubMed: 31579422
- Li SM et al. The putative tumour suppressor miR-1-3p modulates prostate cancer cell aggressiveness by repressing E2F5 and PFTK1. J Exp Clin Cancer Res 37:219 (2018). PubMed: 30185212
- Vuong L et al. Pattern of expression of p53, its family members, and regulators during early ocular development and in the post-mitotic retina. Invest Ophthalmol Vis Sci 53:4821-31 (2012). PubMed: 22714890