Anti-E. coli heat labile toxin B 抗体 [BB12] (ab37204)


  • 製品名Anti-E. coli heat labile toxin B antibody [BB12]
    E. coli heat labile toxin B 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [BB12] to E. coli heat labile toxin B
  • 特異性Esherichia coli heat-labile enterotoxin B-chain.
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Escherichia coli
  • 免疫原

    Recombinant Beta-chain of E. coli heat-labile enterotoxin.


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名BB12
  • アイソタイプIgG2b
  • 研究分野


Our Abpromise guarantee covers the use of ab37204 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 14 kDa.


  • 関連性Escherichia coli heat-labile enterotoxin (LT) is the causative agent of traveller's diarrhoea, and it is also responsible for the deaths of hundreds of thousands of children per year in developing countries. LT is highly homologous in sequence, structure and function to cholera toxin (CT). Both toxins attack intestinal epithelial cells via specific binding to the branched pentasaccharide of ganglioside GM1 at the cell surface. LT is a plasmid-encoded, high molecular weight toxin, the crystalline structure of which revealed that it is composed of one A subunit (LTA) (27 kDa) and five non-covalently associated B subunits (LTB) (11.6 kDa each) forming a ring-like pentamer. The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. The B chain has a membrane binding function. A receptor-binding antagonist which blocked the interaction of LT and CT with cell suface GM1 would potentially constitute a prophylactic drug conferring protection both against the severe effects of cholera itself and against the milder but more common disease caused by LT.
  • 細胞内局在Secreted
  • 参照データベース
    • 別名
      • eltB antibody
      • Heat labile enterotoxin B chain antibody
      • LTB antibody
      • LTH B antibody
      • LTP B antibody
      see all

    Anti-E. coli heat labile toxin B antibody [BB12] (ab37204) 使用論文

    This product has been referenced in:
    • Becker PM  et al. Inhibition of binding of the AB5-type enterotoxins LT-I and cholera toxin to ganglioside GM1 by galactose-rich dietary components. Foodborne Pathog Dis 7:225-33 (2010). ELISA ; Escherichia coli . Read more (PubMed: 19919285) »

    See 1 Publication for this product

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    We would not be able to confirm the DH5alpha specifictiy of ab37204 and ab20976. However we can confirm ab25823 and ab48416 would work with DH5alpha species.

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    I now have further information to share with you from the lab in regards to the anti-E. coli heat labile toxin B antibody [BB12] (ab37204). The lab have retested this antibody as well as the ant...

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    As mentioned previously, I am in contact with the lab over this issue. They are currently looking into this, however they have asked for confirmation of one thing.

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