製品の概要

  • 製品名DYX1C1 peptide

製品の詳細

  • 由来Synthetic

特性

Our Abpromise guarantee covers the use of ab81940 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-DYX1C1 antibody (ab75185)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • Dyslexia susceptibility 1 candidate 1
    • Dyslexia susceptibility 1 candidate gene 1 protein
    • DYX1
    • DYX1C1
    • DYXC1
    • DYXC1_HUMAN
    • EKN1
    • FLJ37882
    • MGC70618
    • RD
    see all
  • 機能Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity.
  • 組織特異性Expressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells.
  • 関連疾患Defects in DYX1C1 may be a cause of susceptibility to dyslexia type 1 (DYX1) [MIM:127700]. A relatively common, complex cognitive disorder characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities. It is a multifactorial trait, with evidence for familial clustering and heritability. Note=A chromosomal aberration involving DYX1C1 has been found in a family affected by dyslexia. Translocation t(2;15)(q11;q21).
  • 配列類似性Contains 1 CS domain.
    Contains 3 TPR repeats.
  • 細胞内局在Nucleus. Cytoplasm.
  • Information by UniProt

DYX1C1 peptide (ab81940) 使用論文

ab81940 has not yet been referenced specifically in any publications.

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