製品の概要

  • 製品名Anti-Dystonin antibody
  • 製品の詳細
    Mouse monoclonal to Dystonin
  • アプリケーション適用あり: Sandwich ELISA, ICC/IF, WB, IHC-Frmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Recombinant fragment: EDKLILAGNA LQSDSKRLES GVQFQNEAEI AGYILECENL LRQHVIDVQI LIDGKYYQAD QLVQRVAKLR DEIMALRNEC SSVYSKGRIL TTEQTKLMIS , corresponding to amino acids 401-501 of Human Dystonin

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab55654 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Sandwich ELISA Use at an assay dependent concentration.
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 1 - 5 µg/ml.
IHC-Fr Use at an assay dependent concentration. PubMed: 18638474

ターゲット情報

  • 関連性Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Isoform 3: plays a structural role in the assembly of hemidesmosomes of epithelial cells; anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. Required for the regulation of keratinocyte polarity and motility; mediates integrin ITGB4 regulation of RAC1 activity. Isoform 6: required for bundling actin filaments around the nucleus By similarity. Isoform 7: regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.
  • 細胞内局在Cytoplasm › cytoskeleton.
  • 参照データベース
  • 別名
    • 230 kDa bullous pemphigoid antigen antibody
    • 230/240 kDa bullous pemphigoid antigen antibody
    • BP230 antibody
    • BP240 antibody
    • BPA antibody
    • BPAG1 antibody
    • Bullous pemphigoid antigen 1 antibody
    • Bullous pemphigoid antigen antibody
    • DMH antibody
    • DST antibody
    • DT antibody
    • Dystonia musculorum protein antibody
    • Hemidesmosomal plaque protein antibody
    • KIAA0728 antibody
    see all

Anti-Dystonin antibody 画像

  • Immunofluorescent staining of HeLa cells using ab55654 at 10 μg/mL.

  • Western blot against tagged recombinant protein immunogen using ab55654 Dystonin antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

Anti-Dystonin antibody (ab55654) 使用論文

This product has been referenced in:
  • Young KG & Kothary R Dystonin/Bpag1 is a necessary endoplasmic reticulum/nuclear envelope protein in sensory neurons. Exp Cell Res 314:2750-61 (2008). IHC-Fr ; Mouse . Read more (PubMed: 18638474) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"