Anti-Dynorphin A 抗体 (ab40647)


  • 製品名Anti-Dynorphin A antibody
    Dynorphin A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Dynorphin A
  • 特異性This antibody shows specificity of: Dynorphin A (1-13) 100%; [Leu5]-Enkephalin 0%; [Met5]-Enkephalin 0% and b-Endorphin (human) 0%.
  • アプリケーション適用あり: IHC-P, ELISA, RIA, ICCmore details
  • 種交差性
    交差種: Human, Pig
    交差が予測される動物種: Mouse, Rat, Guinea pig, Cow, Chimpanzee, Zebrafish, Baboon, Cynomolgus Monkey, Macaque Monkey, Rhesus monkey, Gorilla
  • 免疫原

    Synthetic peptide:


    , corresponding to amino acids 1-13 of Dynorphin A


  • 製品の状態Liquid
  • 保存方法Store at +4°C short term (1-2 weeks) (add antibacterial agent). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: Whole serum
  • 精製度Whole antiserum
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野


Our Abpromise guarantee covers the use of ab40647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ELISA Use at an assay dependent concentration. Cell culture filtrate or whole cells directly coated onto microtitre wells can be used.
RIA Use at an assay dependent concentration.
With this antibody, we have found that blocking with 5% goat or donkey serum significantly reduces background as compared to BSA or milk.
ICC Use at an assay dependent concentration.


  • 関連性Dynorphins are a class of peptides produced by many different populations of neurons, which has some opiate like activity. It is thus classed as an endogenous opioid peptide. The dynorphins, which include dynorphin A, dynorphin B, alpha and beta neoendorphin, and big dynorphin, are all the products of a single gene, 'preprodynorphin'. Dynorphin is produced in many different parts of the brain, including the hypothalamus, the hippocampus and the spinal cord, and has many different physiological actions, depending upon its site of production. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. As such, it may help some individuals against addiction. Blocking dynorphin may help alleviate depression.
  • 細胞内局在Secreted
  • 参照データベース
  • 別名
    • Beta neoendorphin dynorphin antibody
    • Dyn A17 antibody
    • Dynorphin A antibody
    • PDYN antibody
    • Preprodynorphin antibody
    • Proenkephalin B antibody
    see all

Anti-Dynorphin A antibody 画像

  • IHC image of ab40647 staining in human hippocampus formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab40647, 1/1000 dilution, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

    For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Dynorphin A antibody (ab40647) 使用論文

ab40647 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your call yesterday and for your question about these antibodies. I apologize for the delay getting back to you.

We have a general IHC protocol for FFPE sections that includes a section on antigen retrieval-


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