製品の概要

  • 製品名
    Anti-DYNLT3 antibody
  • 製品の詳細
    Rabbit polyclonal to DYNLT3
  • アプリケーション
    適用あり: IHC-P, WB, ICC/IFmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    antigen sequence: DEVGFNAEEA HNIVKECVDG VLGGEDYNHN NINQWTASIV EQSLTHLVKL GKAYKYIVTC AVVQKSAYGF HTASSCFWDT TSDGTCTVRW E, corresponding to amino acids 9-99 of Human DYNLT3.

  • ポジティブ・コントロール
    • U 251 MG cells; RT 4, U 251 MG, Human liver and Human tonsil lysates; Human cerebral cortex tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab121209 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/250.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100.

ターゲット情報

  • 機能
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis.
  • 配列類似性
    Belongs to the dynein light chain Tctex-type family.
  • 細胞内局在
    Nucleus. Cytoplasm > cytoskeleton. Chromosome > centromere > kinetochore. Colocalizes with BUB3 at kinetochores specifically during prometaphase.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2310075M16Rik antibody
    • AU042796 antibody
    • DYLT3_HUMAN antibody
    • Dynein light chain Tctex-type 3 antibody
    • DYNLT3 antibody
    • Protein 91/23 antibody
    • RP23-256J17.2 antibody
    • RP3 antibody
    • T-complex-associated testis-expressed 1-like antibody
    • Tcte1l antibody
    • TCTEX1L antibody
    see all

画像

  • ab121209 at 1/750 dilution staining DYNLT3 in Paraffin-embedded Human cerebral cortex tissue by Immunohistochemistry.
  • All lanes : Anti-DYNLT3 antibody (ab121209) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate
  • ab121209 at 4 µg/ml staining DYNLT3 in PFA/Triton X-100 fixed/permeabilized U 251 MG cells by Immunofluorescence (green).

参考文献

This product has been referenced in:

See all 2 Publications for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab121209.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録