Anti-Dynein intermediate chain 2 抗体 (ab72746)

製品の概要

  • 製品名Anti-Dynein intermediate chain 2 antibody
    Dynein intermediate chain 2 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to Dynein intermediate chain 2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human Dynein intermediate chain 2 protein (AAH39582).

  • ポジティブ・コントロール
    • Dynein intermediate chain 2 transfected 293T cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: Whole serum
  • 精製度Whole antiserum
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab72746 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 69 kDa.

ターゲット情報

  • 機能Part of the dynein complex of respiratory cilia.
  • 組織特異性Highly expressed in trachea and testis.
  • 関連疾患Defects in DNAI2 are the cause of primary ciliary dyskinesia type 9 (CILD9) [MIM:612444]. CILD is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
  • 配列類似性Belongs to the dynein intermediate chain family.
    Contains 5 WD repeats.
  • 細胞内局在Cytoplasm > cytoskeleton > cilium axoneme.
  • Information by UniProt
  • 参照データベース
  • 別名
    • axonemal antibody
    • Axonemal dynein intermediate chain 2 antibody
    • CILD9 antibody
    • DNAI 2 antibody
    • Dnai2 antibody
    • DNAI2_HUMAN antibody
    • Dynein axonemal intermediate chain 2 antibody
    • Dynein axonemal intermediate polypeptide 2 antibody
    • Dynein intermediate chain 2 antibody
    • Dynein intermediate chain 2 axonemal antibody
    see all

Anti-Dynein intermediate chain 2 antibody 画像

  • All lanes : Anti-Dynein intermediate chain 2 antibody (ab72746) at 1/500 dilution

    Lane 1 : Dynein intermediate chain 2 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 69 kDa
    Observed band size : 69 kDa

Anti-Dynein intermediate chain 2 antibody (ab72746) 使用論文

ab72746 has not yet been referenced specifically in any publications.

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