Anti-Dynein intermediate chain 2 抗体 (ab108237)

製品の概要

  • 製品名Anti-Dynein intermediate chain 2 antibody
    Dynein intermediate chain 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Dynein intermediate chain 2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 71-120 (TRGVNHVEGG WPKDVNPLEL EQTIRFRKKV EKDENYVNAI MQLGSIMEHC) of Human Dynein intermediate chain 2 (NP_075462).

  • ポジティブ・コントロール
    • PANC1 cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab108237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 69 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Part of the dynein complex of respiratory cilia.
  • 組織特異性Highly expressed in trachea and testis.
  • 関連疾患Defects in DNAI2 are the cause of primary ciliary dyskinesia type 9 (CILD9) [MIM:612444]. CILD is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
  • 配列類似性Belongs to the dynein intermediate chain family.
    Contains 5 WD repeats.
  • 細胞内局在Cytoplasm > cytoskeleton > cilium axoneme.
  • Information by UniProt
  • 参照データベース
  • 別名
    • axonemal antibody
    • Axonemal dynein intermediate chain 2 antibody
    • CILD9 antibody
    • DNAI 2 antibody
    • Dnai2 antibody
    • DNAI2_HUMAN antibody
    • Dynein axonemal intermediate chain 2 antibody
    • Dynein axonemal intermediate polypeptide 2 antibody
    • Dynein intermediate chain 2 antibody
    • Dynein intermediate chain 2 axonemal antibody
    see all

Anti-Dynein intermediate chain 2 antibody 画像

  • Anti-Dynein intermediate chain 2 antibody (ab108237) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 69 kDa

Anti-Dynein intermediate chain 2 antibody (ab108237) 使用論文

ab108237 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"