Anti-p50 dynamitin 抗体 [EPR5094] (ab109752)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR5094] to p50 dynamitin
- Suitable for: WB, Flow Cyt (Intra)
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-p50 dynamitin antibody [EPR5094]
p50 dynamitin 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR5094] to p50 dynamitin -
由来種
Rabbit -
アプリケーション
適用あり: WB, Flow Cyt (Intra)more details
適用なし: ICC/IF or IHC-P -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- MCF7, A375, Saos2, and SH SY5Y cell lysates; Saos2 cells.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR5094 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab109752の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/10000 - 1/50000. Predicted molecular weight: 44 kDa.
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Flow Cyt (Intra) |
1/10 - 1/100.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
特記事項 |
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WB
1/10000 - 1/50000. Predicted molecular weight: 44 kDa. |
Flow Cyt (Intra)
1/10 - 1/100. ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development. -
配列類似性
Belongs to the dynactin subunit 2 family. -
細胞内局在
Cytoplasm > cytoskeleton > centrosome. Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 10540 Human
- Entrez Gene: 69654 Mouse
- Entrez Gene: 299850 Rat
- Omim: 607376 Human
- SwissProt: Q13561 Human
- SwissProt: Q99KJ8 Mouse
- SwissProt: Q6AYH5 Rat
- Unigene: 289123 Human
see all -
別名
- 50 kD dynein associated polypeptide antibody
- 50 kDa dynein associated polypeptide antibody
- 50 kDa dynein-associated polypeptide antibody
see all
画像
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All lanes : Anti-p50 dynamitin antibody [EPR5094] (ab109752) at 1/10000 dilution
Lane 1 : MCF7 cell lysate
Lane 2 : A375 cell lysate
Lane 3 : Saos2 cell lysate
Lane 4 : SH SY5Y cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 44 kDa -
ab109752 at 1/10 dilution staining p50 dynamitin in Saos2 cells by intracellular flow cytometry (red) or a rabbit IgG (negative) (green).
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab109752 は 2 報の論文で使用されています。
- Zhou H et al. Ginseng polysaccharide inhibits MDA-MB-231 cell proliferation by activating the inflammatory response. Exp Ther Med 20:229 (2020). PubMed: 33149784
- Valle-Tenney R et al. Dynein Regulators Are Important for Ecotropic Murine Leukemia Virus Infection. J Virol 90:6896-6905 (2016). PubMed: 27194765