The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/1000. Detects a band of approximately 98 kDa (predicted mouse molecular weight: 98 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
Belongs to the dynamin family. Contains 1 GED domain. Contains 1 PH domain.
Reis CR et al. Crosstalk between Akt/GSK3ß signaling and dynamin-1 regulates clathrin-mediated endocytosis. EMBO J34:2132-46 (2015).
Read more (PubMed: 26139537) »
Mori H et al. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin ß1. Development140:343-52 (2013).
Read more (PubMed: 23250208) »