Anti-Dynamin 1 (phospho S774) 抗体 (ab55324)
Key features and details
- Rabbit polyclonal to Dynamin 1 (phospho S774)
- Suitable for: ELISA, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-Dynamin 1 (phospho S774) antibody
Dynamin 1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Dynamin 1 (phospho S774) -
由来種
Rabbit -
アプリケーション
適用あり: ELISA, WBmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human Dynamin 1 aa 700-800 (phospho S774).
Database link: Q05193 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab55324の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration.
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WB | (1) |
1/500 - 1/1000. Detects a band of approximately 98 kDa (predicted molecular weight: 98 kDa).
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特記事項 |
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ELISA
Use at an assay dependent concentration. |
WB
1/500 - 1/1000. Detects a band of approximately 98 kDa (predicted molecular weight: 98 kDa). |
ターゲット情報
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機能
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis. -
配列類似性
Belongs to the dynamin family.
Contains 1 GED domain.
Contains 1 PH domain. -
細胞内局在
Cytoplasm. Cytoplasm > cytoskeleton. Microtubule-associated. - Information by UniProt
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参照データベース
- Entrez Gene: 1759 Human
- Entrez Gene: 13429 Mouse
- Entrez Gene: 140694 Rat
- Omim: 602377 Human
- SwissProt: Q05193 Human
- SwissProt: P39053 Mouse
- SwissProt: P21575 Rat
- Unigene: 522413 Human
see all -
別名
- B dynamin antibody
- D100 antibody
- DNM 1 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (6)
ab55324 は 6 報の論文で使用されています。
- Du JJ et al. Clathrin-independent but dynamin-dependent mechanisms mediate Ca2+-triggered endocytosis of the glutamate GluK2 receptor upon excitotoxicity. J Integr Neurosci 19:449-458 (2020). PubMed: 33070524
- Priya R et al. Activity Regulates Cell Death within Cortical Interneurons through a Calcineurin-Dependent Mechanism. Cell Rep 22:1695-1709 (2018). WB ; Mouse . PubMed: 29444424
- Chen PH et al. Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis. Dev Cell 40:278-288.e5 (2017). PubMed: 28171750
- Reis CR et al. Crosstalk between Akt/GSK3ß signaling and dynamin-1 regulates clathrin-mediated endocytosis. EMBO J 34:2132-46 (2015). PubMed: 26139537
- Mori H et al. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin ß1. Development 140:343-52 (2013). WB ; Mouse . PubMed: 23250208
- Martins-de-Souza D et al. Phosphoproteomic differences in major depressive disorder postmortem brains indicate effects on synaptic function. Eur Arch Psychiatry Clin Neurosci 262:657-66 (2012). WB ; Human . PubMed: 22350622