製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Dux4
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 253-283 of Human Dux4 (Q9UBX2).

  • ポジティブ・コントロール
    • HL-60 cell line lysates.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    Purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab110555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 45 kDa.

ターゲット情報

  • 関連性
    DUX4 is a homeodomain protein with a similar protein sequence to Pax3 and Pax7. Defects in DUX4 may be the cause of facioscapulohumeral muscular dystrophy (FSHD). FSHD is characterized by weakness of the muscles of the face, upper-arm and shoulder girdle. Severity is highly variable. Weakness is slowly progressive and about 20% of affected individuals eventually require a wheelchair. Approximately 70-90% of individuals have inherited the disease-causing deletion from a parent, and approximately 10-30% of affected individuals have FSHD as the result of a de novo deletion. Offsprings of an affected individual have a 50% chance of inheriting the deletion.
  • 細胞内局在
    Nuclear
  • 参照データベース
  • 別名
    • Double homeobox 4 antibody
    • Double homeobox protein 10 antibody
    • Double homeobox protein 4 antibody
    • Double homeobox protein 4/10 antibody
    • DUX10 antibody
    • DUX4L antibody
    • DUX4L1 antibody
    see all

画像

  • Anti-Dux4 antibody (ab110555) at 1/100 dilution + HL-60 cell line lysate at 35 µg

    Predicted band size : 45 kDa

プロトコール

参考文献

ab110555 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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