製品の概要

  • 製品名Anti-DUT antibody
    DUT 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DUT
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to a sequence mapping at the middle region of human DUT-N, identical to the related rat and mouse sequence.

  • ポジティブ・コントロール
    • Rat cardiac muscle tissue lysate and rat cardiac muscle tissue.

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab65971 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報IHC-P: Use at a concentration of 1 - 2 µg/ml. Boiling the sections is required.
    WB: Use at a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: ~23 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
    • 組織特異性Found in a variety of tissues.
    • パスウェイPyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.
    • 配列類似性Belongs to the dUTPase family.
    • 翻訳後修飾Phosphorylation in mature T-cells occur in a cell cycle-dependent manner.
    • 細胞内局在Mitochondrion and Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Deoxyuridine 5' triphosphate nucleotidohydrolase, nuclear isoform antibody
      • Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial antibody
      • Deoxyuridine triphosphatase antibody
      • dut antibody
      • DUT_HUMAN antibody
      • dUTP nucleotidohydrolase antibody
      • dUTP pyrophosphatase antibody
      • dUTPase antibody
      • FLJ20622 antibody
      see all

    Anti-DUT antibody 画像

    • ab65971 at 1µg/ml staining DUT-N in the cytoplasm of paraffin-embedded rat tissue sections (cardiac muscle). (DAB chromogenic reaction)
    • Anti-DUT antibody (ab65971) at 0.5 µg/ml + Rat cardiac muscle tissue lysate

      Predicted band size : 23 kDa
      Observed band size : 54 kDa (why is the actual band size different from the predicted?)

    Anti-DUT antibody (ab65971) 使用論文

    This product has been referenced in:
    • Luo Y  et al. Uracil incorporation into genomic DNA does not predict toxicity caused by chemotherapeutic inhibition of thymidylate synthase. DNA Repair (Amst) 7:162-9 (2008). Read more (PubMed: 17942376) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab65971.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"