Anti-DUSP4 抗体 [2295E1a] (ab53753)

製品の概要

• 製品名
  Anti-DUSP4 antibody [2295E1a]
  DUSP4 一次抗体 製品一覧
• 製品の詳細
  Mouse monoclonal [2295E1a] to DUSP4
• アプリケーション
  適用あり: WB, Dot blotmore details
• 種交差性
  交差種: Recombinant fragment
  交差が予測される動物種: Human
• 免疫原

  Recombinant fragment: corresponding to an internal sequence from Human DUSP4.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C.
• バッファー
  Preservative: 0.05% Sodium Azide
  Constituents: 1% BSA, PBS, pH 7.4
• Concentration information loading...
• 精製度
  Protein G purified
• 特記事項（精製）
  This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
• ポリ/モノ
  モノクローナル
• クローン名
  2295E1a
• アイソタイプ
  IgG1
• 研究分野
  • Cell Biology
  • Cell Cycle
  • Kinases/Phosphatases
  • Phosphatases

  • Signal Transduction
  • Protein Phosphorylation
  • Tyrosine Phosphatases

  • Signal Transduction
  • Protein Phosphorylation
  • Ser / Thr Phosphatases

関連製品

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

アプリケーション

ターゲット情報

• 機能
  Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
• 配列類似性
  Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
  Contains 1 rhodanese domain.
  Contains 1 tyrosine-protein phosphatase domain.
• 翻訳後修飾
  Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein.
• 細胞内局在
  Nucleus.

• Target information above from: UniProt accession Q13115 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 1846 Human
  • Omim: 602747 Human
  • SwissProt: Q13115 Human
  • Unigene: 417962 Human
• 別名
  • Dual specificity phosphatase 4 antibody
  • Dual specificity protein phosphatase 4 antibody
  • Dual specificity protein phosphatase hVH2 antibody

  • DUS4_HUMAN antibody
  • DUSP 4 antibody
  • Dusp4 antibody
  • HVH 2 antibody
  • HVH2 antibody
  • MAP kinase phosphatase 2 antibody
  • Mitogen activated protein kinase phosphatase 2 antibody
  • Mitogen-activated protein kinase phosphatase 2 antibody
  • MKP 2 antibody
  • MKP-2 antibody
  • MKP2 antibody
  • Serine/threonine specific protein phosphatase antibody
  • TYP antibody
  • Typ1 antibody
  • VH 2 antibody
  • VH1 homologous phosphatase 2 antibody
  • VH2 antibody

  see all

プロトコール

• Western blot protocols