製品の概要

  • 製品名Anti-DTX2 antibody
    DTX2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DTX2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Xenopus laevis, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 454-503 (EDCGTILIVY SIPHGIQGPE HPNPGKPFTA RGFPRQCYLP DNAQGRKVLE) of Human DTX2(NP_001096066).

  • ポジティブ・コントロール
    • HepG2 cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーConstituents: 98% PBS, 2% Sucrose
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab106332 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 62 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Belongs to the Deltex family.
    Contains 1 RING-type zinc finger.
    Contains 2 WWE domains.
  • ドメインThe WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases.
  • 細胞内局在Cytoplasm. Nucleus. Predominantly cytoplasmic. Partially nuclear.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Deltex 2 antibody
    • deltex homolog 2 (Drosophila) antibody
    • deltex, Drosophila, homolog of, 2 antibody
    • Deltex2 antibody
    • DTX2 antibody
    • DTX2_HUMAN antibody
    • hDTX2 antibody
    • Highly similar to hPMSR6 [H.sapiens] antibody
    • KIAA1528 antibody
    • Probable E3 ubiquitin-protein ligase DTX2 antibody
    • Protein deltex 2 antibody
    • Protein deltex-2 antibody
    • RING finger protein 58 antibody
    • RNF58 antibody
    • Zinc ion binding protein antibody
    see all

Anti-DTX2 antibody 画像

  • Anti-DTX2 antibody (ab106332) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 62 kDa

Anti-DTX2 antibody (ab106332) 使用論文

ab106332 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"