製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to DRIP130
  • アプリケーション
    適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Turkey, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide, corresponding to a region between amino acids 1-50 of Human DRIP130 (SwissProt Q9ULK4)

  • ポジティブ・コントロール
    • Nuclear extract from HeLa cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70447 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP
  • 追加情報
    IP: Use at 1 - 4 µg/mg of lysate.


    Is unsuitable for WB.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Required for transcriptional activation subsequent to the assembly of the preinitiation complex (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling.
    • 配列類似性
      Belongs to the Mediator complex subunit 23 family.
    • 細胞内局在
      Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 130 kDa transcriptional co activator antibody
      • 133 kDa transcriptional co activator antibody
      • Activator recruited cofactor 130 kDa component antibody
      • Activator-recruited cofactor 130 kDa component antibody
      • ARC 130 antibody
      • ARC130 antibody
      • Cofactor required for Sp1 transcriptional activation subunit 3 130kDa antibody
      • Cofactor required for Sp1 transcriptional activation subunit 3 130kDa mediator antibody
      • Cofactor required for Sp1 transcriptional activation subunit 3 antibody
      • CRSP 130 antibody
      • CRSP 130 kD subunit antibody
      • CRSP 133 antibody
      • CRSP 3 antibody
      • CRSP complex subunit 3 antibody
      • CRSP130 antibody
      • CRSP133 antibody
      • CRSP3 antibody
      • CRSP3 protein antibody
      • DKFZp434H0117 antibody
      • DRIP 130 antibody
      • DRIP130 antibody
      • hSur-2 antibody
      • KIAA1216 antibody
      • MED 23 antibody
      • med23 antibody
      • MED23_HUMAN antibody
      • Mediator complex subunit 23 antibody
      • Mediator of RNA polymerase II transcription subunit 23 antibody
      • MRT18 antibody
      • Protein sur-2 homolog antibody
      • SUR 2 antibody
      • SUR2 antibody
      • Transcriptional co activator CRSP 130 antibody
      • Transcriptional co activator CRSP130 antibody
      • Transcriptional coactivator CRSP130 antibody
      • Vitamin D3 receptor interacting protein antibody
      • Vitamin D3 receptor interacting protein complex 130 kDa component antibody
      • Vitamin D3 receptor-interacting protein complex 130 kDa component antibody
      see all

    画像

    • Detection of Human DRIP130 by Immunoprecipitation in Nuclear extract (5 mg) from HeLa cells using ab70447 at 4 µg/5 mg extract. Detection: Coomassie blue stain.

    プロトコール

    参考文献

    ab70447 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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