製品の概要

  • 製品名
    Anti-DRAM2 antibody
  • 製品の詳細
    Rabbit polyclonal to DRAM2
  • アプリケーション
    適用あり: IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence: ISLRVEANLH GLTLYDTAPC PINNERTRLL SRDI, corresponding to C terminal amino acids 233-266 of Human DRAM2.

  • ポジティブ・コントロール
    • Human small intestine tissue; Human U 2 OS cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab121554 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. Recommended fixation/permeabilization: PFA/Triton X-100

ターゲット情報

  • 機能
    Induces apoptotic cell death when co-expressed with DRAM1.
  • 組織特異性
    Expression is down-regulated in ovarian tumors (at protein level). Widely expressed with highest levels in placenta and heart. Not detected in brain or thymus.
  • 配列類似性
    Belongs to the DRAM/TMEM150 family.
  • 細胞内局在
    Lysosome membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2010305N14Rik antibody
    • 2610318G18Rik antibody
    • AI647667 antibody
    • damage regulated autophagy modulator 2 antibody
    • DNA damage regulated autophagy modulator 2 antibody
    • DNA damage regulated autophagy modulator protein 2 antibody
    • DNA damage-regulated autophagy modulator protein 2 antibody
    • Dram2 antibody
    • DRAM2_HUMAN antibody
    • PRO180 antibody
    • PSEC0031 antibody
    • RP5-1180E21.1 antibody
    • Tmem77 antibody
    • Transmembrane protein 77 antibody
    • WWFQ154 antibody
    see all

画像

  • ab121554 at 1/100 dilution staining DRAM2 in Paraffin-embedded Human small intestine tissue by Immunohistochemistry.
    Note: granular cytoplasmic positivity in glandular cells.
  • ab121554 at 4 µg/ml staining DRAM2 in PFA/Triton X-100 fixed/permeabilized U2 OS cells by Immunofluorescence (green).
    Note: positivity in golgi apparatus & vesicles.

参考文献

ab121554 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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