Anti-DR6 抗体 [DR-6-04-EC] (Phycoerythrin) (ab52513)

製品の概要

  • 製品名
    Anti-DR6 antibody [DR-6-04-EC] (Phycoerythrin)
    DR6 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [DR-6-04-EC] to DR6 (Phycoerythrin)
  • 標識
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Fusion protein, corresponding to amino acids 42-335 (extracellular region) of Human DR6 linked to the Fc portion of Human IgG1

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    Preservative: 15mM Sodium Azide
    Constituents: 0.2% BSA, PBS
  • Concentration information loading...
  • 精製度
    Size exclusion
  • 特記事項(精製)
    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
  • ポリ/モノ
    モノクローナル
  • クローン名
    DR-6-04-EC
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab52513 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報
    Flow Cyt: A concentration of 10µg/ml is recommended as starting point this product.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
    • 組織特異性
      Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes.
    • 配列類似性
      Contains 1 death domain.
      Contains 4 TNFR-Cys repeats.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • TNFRSF 21 antibody
      • BM 018 antibody
      • BM018 antibody
      • CD358 antibody
      • Death receptor 6 antibody
      • DR 6 antibody
      • DR6 antibody
      • MGC31965 antibody
      • OTTHUMP00000039915 antibody
      • TNFR related death receptor 6 antibody
      • TNFRSF21 antibody
      • TNFRSF21 protein antibody
      • TNR21_HUMAN antibody
      • Tumor necrosis factor receptor superfamily member 21 antibody
      • Tumor necrosis factor receptor superfamily member 21 precursor antibody
      see all

    プロトコール

    参考文献

    ab52513 has not yet been referenced specifically in any publications.

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    There are currently no Customer reviews or Questions for ab52513.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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