Anti-DR5 抗体 [DR5-01-1] (Phycoerythrin) (ab55863)

製品の概要

  • 製品名
    Anti-DR5 antibody [DR5-01-1] (Phycoerythrin)
    DR5 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [DR5-01-1] to DR5 (Phycoerythrin)
  • 標識
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特異性
    This recognizes an extracellular domain of TRAIL R2 (DR5).
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fusion protein of human IgG heavy chain and an extracellular domain of DR5 (TRAIL R2) (Human).

  • ポジティブ・コントロール
    • JURKAT human peripheral blood leukemia T cell line.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab55863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報
    Flow Cyt: Use at a concentration of 5.0 µg/ml. This dilution is a recommended starting point for use of this product. Working concentrations should be determined by the end user.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
    • 組織特異性
      Widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines such as HeLaS3, K-562, HL-60, SW480, A-549 and G-361; highly expressed in heart, peripheral blood lymphocytes, liver, pancreas, spleen, thymus, prostate, ovary, uterus, placenta, testis, esophagus, stomach and throughout the intestinal tract; not detectable in brain.
    • 関連疾患
      Squamous cell carcinoma of the head and neck
    • 配列類似性
      Contains 1 death domain.
      Contains 3 TNFR-Cys repeats.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Fas like protein antibody
      • Apoptosis inducing protein TRICK2A/2B antibody
      • Apoptosis inducing receptor TRAIL R2 antibody
      • CD262 antibody
      • CD262 antigen antibody
      • Cytotoxic TRAIL receptor 2 antibody
      • Death domain containing receptor for TRAIL/Apo 2L antibody
      • Death receptor 5 antibody
      • DR5 antibody
      • KILLER antibody
      • KILLER/DR5 antibody
      • OTTHUMP00000123492 antibody
      • OTTHUMP00000123493 antibody
      • p53 regulated DNA damage inducible cell death receptor(killer) antibody
      • TNF related apoptosis inducing ligand receptor 2 antibody
      • TNF-related apoptosis-inducing ligand receptor 2 antibody
      • TNFRSF10B antibody
      • TR10B_HUMAN antibody
      • TRAIL R2 antibody
      • TRAIL receptor 2 antibody
      • TRAIL-R2 antibody
      • TRAILR2 antibody
      • TRICK2 antibody
      • TRICK2A antibody
      • TRICK2B antibody
      • TRICKB antibody
      • Tumor necrosis factor receptor like protein ZTNFR9 antibody
      • Tumor necrosis factor receptor superfamily member 10B antibody
      • Tumor necrosis factor receptor superfamily, member 10b antibody
      • ZTNFR9 antibody
      see all

    プロトコール

    参考文献

    ab55863 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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