Anti-DR3 抗体 (ab8411)

製品の概要

• 製品名
  Anti-DR3 antibody
  DR3 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to DR3
• 特異性
  Does not recognise other death receptors.
• アプリケーション
  適用あり: WBmore details
• 種交差性
  交差種: Mouse, Rat, Human
  
• 免疫原

  Synthetic peptide, corresponding to C terminal amino acids 398-417 of Human DR3 (Peptide available as ab8443.)

• ポジティブ･コントロール
  • Jurkat total cell lysate A 59 kDa band should bedetected.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at +4°C.
• バッファー
  PBS with 0.02% sodium azide
• Concentration information loading...
• 精製度
  IgG fraction
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 軽鎖の種類
  unknown
• 研究分野
  • Cell Biology
  • Apoptosis
  • Receptors
  • Death Receptors

  • Signal Transduction
  • Signaling Pathway
  • Nuclear Signaling
  • NFkB Pathway

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Immunizing Peptide (Blocking)
  • Human DR3 peptide (ab8443)
• Positive Controls
  • Jurkat whole cell lysate (ab7899)

アプリケーション

ターゲット情報

• 機能
  Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
• 組織特異性
  Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
• 配列類似性
  Contains 1 death domain.
  Contains 4 TNFR-Cys repeats.
• 翻訳後修飾
  Glycosylated.
• 細胞内局在
  Secreted and Cell membrane.

• Target information above from: UniProt accession Q93038 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 8718 Human
  • Entrez Gene: 85030 Mouse
  • Entrez Gene: 500592 Rat
  • Omim: 603366 Human
  • SwissProt: Q93038 Human
  • Unigene: 462529 Human
  • Unigene: 101198 Mouse
  • Unigene: 106560 Rat
• 別名
  • Apo 3 antibody
  • Apo-3 antibody
  • Apo3 antibody

  • Apoptosis inducing receptor AIR antibody
  • Apoptosis inducing receptor antibody
  • Apoptosis mediating receptor antibody
  • Apoptosis mediating receptor DR 3 antibody
  • Apoptosis mediating receptor DR3 antibody
  • Apoptosis mediating receptor TRAMP antibody
  • Apoptosis-inducing receptor AIR antibody
  • Apoptosis-mediating receptor DR3 antibody
  • Apoptosis-mediating receptor TRAMP antibody
  • DDR 3 antibody
  • DDR3 antibody
  • Death domain receptor 3 antibody
  • Death domain receptor 3 soluble form antibody
  • Death receptor 3 antibody
  • Death receptor beta antibody
  • DR 3 antibody
  • DR3 antibody
  • LARD antibody
  • Lymphocyte associated receptor of death antibody
  • Lymphocyte-associated receptor of death antibody
  • Protein WSL antibody
  • Protein WSL-1 antibody
  • TNF receptor superfamily member 25 antibody
  • TNFR25 antibody
  • TNFRSF 12 antibody
  • TNFRSF 25 antibody
  • TNFRSF12 antibody
  • TNFRSF12, formerly antibody
  • TNFRSF25 antibody
  • TNR25_HUMAN antibody
  • TR 3 antibody
  • TR3 antibody
  • TRAMP antibody
  • Translocating chain association membrane protein antibody
  • Tumor necrosis factor receptor superfamily member 12 antibody
  • Tumor necrosis factor receptor superfamily member 25 antibody
  • Tumor necrosis factor receptor superfamily, member 12 (translocating chain association membrane protein) antibody
  • Tumor necrosis factor receptor superfamily, member 12, formerly antibody
  • WSL 1 antibody
  • WSL antibody
  • WSL LR antibody
  • WSL protein antibody
  • WSL1 antibody
  • WSL1 protein antibody
  • WSLLR antibody

  see all

プロトコール

• Western blot protocols