製品の概要

  • 製品名
    Anti-DR1 antibody - Azide free
    DR1 一次抗体 製品一覧
  • 製品の詳細
    Chicken polyclonal to DR1 - Azide free
  • 特異性
    This antibody is specific for Hypothetical protein DKFZp666G145.
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-176 of Hypothetical protein DKFZp666G145.

  • ポジティブ・コントロール
    • Hela cells and 293 cell line.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab37663 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000. Detects a band of approximately 22 kDa (predicted molecular weight: 19 kDa).

ターゲット情報

  • 機能
    The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
  • 配列類似性
    Belongs to the NC2 beta/DR1 family.
    Contains 1 histone-fold domain.
  • 翻訳後修飾
    Phosphorylation regulates its interaction with TBP. Not phosphorylated when bound to DRAP1.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Down regulator of transcription 1 antibody
    • Down regulator of transcription 1 TBP binding antibody
    • Down-regulator of transcription 1 antibody
    • down-regulator of transcription 1, TBP-binding (negative cofactor 2) antibody
    • DR 1 antibody
    • Dr1 antibody
    • Dr1 protein antibody
    • NC 2 antibody
    • NC2 antibody
    • NC2 beta antibody
    • NC2-beta antibody
    • NC2B_HUMAN antibody
    • Negative co factor 2 antibody
    • Negative cofactor 2 antibody
    • Negative cofactor 2 beta antibody
    • Negative cofactor 2-beta antibody
    • Protein Dr1 antibody
    • TATA binding protein associated phosphoprotein antibody
    • TATA box/binding protein associated phosphoprotein DR1 antibody
    • TATA-binding protein-associated phosphoprotein antibody
    see all

画像

  • Lane 1 : Anti-DR1 antibody - Azide free (ab37663) at 1/2000 dilution
    Lanes 2 - 3 : Anti-DR1 antibody - Azide free (ab37663) at 1/500 dilution

    Lane 1 : E coli-derived fusion protein
    Lane 2 : 293 cell line.
    Lane 3 : Hela cells line.

    Secondary
    Goat anti-IgY-HRP. at 1/1000 dilution

    Predicted band size : 19 kDa
    Observed band size : 22 kDa (why is the actual band size different from the predicted?)

プロトコール

参考文献

ab37663 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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