製品の概要

  • 製品名Anti-DR1 antibody
    DR1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to DR1
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Full length Human DR1 (NP_001929.1).

  • ポジティブ・コントロール
    • WB: PC12, Raw 264.7, Jurkat, NIH/3T3 and HeLa nuclear cell lysates; DR1 transfected 293T cell lysate; ICC/IF: HeLa cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88597 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).
ICC/IF Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
  • 配列類似性Belongs to the NC2 beta/DR1 family.
    Contains 1 histone-fold domain.
  • 翻訳後修飾Phosphorylation regulates its interaction with TBP. Not phosphorylated when bound to DRAP1.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Down regulator of transcription 1 antibody
    • Down regulator of transcription 1 TBP binding antibody
    • Down-regulator of transcription 1 antibody
    • down-regulator of transcription 1, TBP-binding (negative cofactor 2) antibody
    • DR 1 antibody
    • Dr1 antibody
    • Dr1 protein antibody
    • NC 2 antibody
    • NC2 antibody
    • NC2 beta antibody
    • NC2-beta antibody
    • NC2B_HUMAN antibody
    • Negative co factor 2 antibody
    • Negative cofactor 2 antibody
    • Negative cofactor 2 beta antibody
    • Negative cofactor 2-beta antibody
    • Protein Dr1 antibody
    • TATA binding protein associated phosphoprotein antibody
    • TATA box/binding protein associated phosphoprotein DR1 antibody
    • TATA-binding protein-associated phosphoprotein antibody
    see all

Anti-DR1 antibody 画像

  • Anti-DR1 antibody (ab88597) at 1 µg/ml + PC12 cell lysate at 50 µg

    Predicted band size : 20 kDa
    Observed band size : 20 kDa
    Additional bands at : 26 kDa. We are unsure as to the identity of these extra bands.
  • Anti-DR1 antibody (ab88597) at 1 µg/ml + HeLa nuclear cell lysate at 50 µg

    Predicted band size : 20 kDa
    Observed band size : 20 kDa
  • Anti-DR1 antibody (ab88597) at 1 µg/ml + Raw 264.7 cell lysate at 50 µg

    Predicted band size : 20 kDa
    Observed band size : 20 kDa
  • Anti-DR1 antibody (ab88597) at 1 µg/ml + Jurkat cell lysate at 50 µg

    Predicted band size : 20 kDa
    Observed band size : 20 kDa
    Additional bands at : 65 kDa. We are unsure as to the identity of these extra bands.
  • Anti-DR1 antibody (ab88597) at 1 µg/ml + NIH3T3 cell lysate at 50 µg

    Predicted band size : 20 kDa
    Observed band size : 20 kDa
  • All lanes : Anti-DR1 antibody (ab88597) at 1 µg/ml

    Lane 1 : DR1 transfected 293T lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 20 kDa
    Observed band size : 20 kDa
  • ab88597 at 10µg/ml staining DR1 in HeLa cells by Immunofluorescence.

Anti-DR1 antibody (ab88597) 使用論文

This product has been referenced in:
  • Sun Z  et al. Functional divergence of the rapidly evolving miR-513 subfamily in primates. BMC Evol Biol 13:255 (2013). WB ; Human . Read more (PubMed: 24252134) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"