製品の概要

  • 製品名
    Anti-DPY19L2 antibody
  • 製品の詳細
    Rabbit polyclonal to DPY19L2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide derived from within residues: IGEFNNLPQE ELLQWIKYST TSDAVFAGAM PTMASIKLST LHPIVNHPHY, corresponding to amino acids 612 - 661 of Human DPY19L2 (NP_776173)

  • ポジティブ・コントロール
    • Fetal heart lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab87596 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 87 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Required during spermatogenesis for sperm head elongation and acrosome formation.
  • 組織特異性
    Widely expressed with high expression in testis. Not detectable in ejaculated sperm (at protein level).
  • 関連疾患
    Defects in DPY19L2 are a cause of globozoospermia (GLOBZOOS) [MIM:102530]. An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome. In the most severe cases the acrosome is totally absent. Globozoospermia is also characterized by abnormal nuclear shape as well as abnormal arrangement of the mitochondria of the spermatozoon. Note=Deletions in DPY19L2 are probably the major cause of GLOBZOOS.
  • 配列類似性
    Belongs to the dpy-19 family.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • D19L2_HUMAN antibody
    • dpy 19 like 2 antibody
    • dpy 19 like 2 (C. elegans) antibody
    • Dpy 19 like protein 2 antibody
    • Dpy-19-like protein 2 antibody
    • dpy19 antibody
    • DPY19L2 antibody
    • FLJ32949 antibody
    • FLJ36166 antibody
    • Protein dpy 19 homolog 2 antibody
    • Protein dpy-19 homolog 2 antibody
    see all

Anti-DPY19L2 antibody 画像

  • Anti-DPY19L2 antibody (ab87596) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal heart lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 87 kDa

プロトコール

Anti-DPY19L2 antibody (ab87596) 使用論文

ab87596 has not yet been referenced specifically in any publications.

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