製品の概要

  • 製品名
    Anti-DPH3 antibody
  • 製品の詳細
    Rabbit polyclonal to DPH3
  • アプリケーション
    適用あり: IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence: EDFQYDEDSE TYFYPCPCGD NFSITKEDLE NGEDVATCPS CSLIIKVIYD KDQFVCGETV PAPSANKELV K, corresponding to amino acids 11-81 of Human DPH3.

  • ポジティブ・コントロール
    • Human spleen tissue; Human cell line U-2 OS
  • 特記事項


    ab122265 is mono-specific.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 一次抗体 備考
    ab122265 is mono-specific.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab122265 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

ターゲット情報

  • 機能
    Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A.
    Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5.
  • 組織特異性
    Widely expressed with highest levels in small intestine, spleen, thymus, heart, liver and lung.
  • 配列類似性
    Belongs to the DPH3 family.
    Contains 1 DPH-type zinc finger.
  • 細胞内局在
    Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CSL-type zinc finger-containing protein 2 antibody
    • Deafness locus putative guanine nucleotide exchange factor interacting protein 1 antibody
    • DelGEF-interacting protein 1 antibody
    • DELGIP antibody
    • DelGIP1 antibody
    • DESR1 antibody
    • Diphtheria toxin and Pseudomonas exotoxin A sensitivity required gene 1 antibody
    • DPH3 antibody
    • DPH3 homolog antibody
    • DPH3 KTI11 homolog antibody
    • DPH3_HUMAN antibody
    • DPH3A antibody
    • KTI11 antibody
    • MGC20197 antibody
    • ZCSL2 antibody
    • Zinc finger CSL domain containing 2 antibody
    • Zinc finger CSL type containing 2 antibody
    see all

画像

  • ab122265, at 4µg/ml, staining DPH3 in Human cell line U-2 OS by Immunofluorescence. Antibody staining is shown in green.
  • ab122265, at 1/50 dilution, staining DPH3 in paraffin-embedded Human spleen tissue by Immunohistochemistry.

参考文献

ab122265 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab122265.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録