DPDPE, delta opioid receptor agonist (ab120675)
Key features and details
- Potent, selective δ opioid receptor agonist
- CAS Number: 88373-73-3
- Purity: > 95%
- Soluble in water to 1 mg/ml
- Form / State: Solid
- Source: Synthetic
製品の概要
-
製品名
DPDPE, delta opioid receptor agonist -
製品の詳細
Potent, selective δ opioid receptor agonist -
別名
- [D-Pen2,5]Enkephalin
-
生理活性の詳細
Potent and selective δ opioid receptor agonist (Ki values are 14, >1000 and >1000 nM for opioid receptor subtypes δ, κ and μ, respectively). Centrally active following systemic administration.
-
精製度
> 95% -
CAS 番号
88373-73-3 -
構造式
製品の特性
-
分子量
645.79 -
分子式
C30H39N5O7S2 -
配列
YXGFX (Modifications: X-2 = D-Pen; X-5 = D-Pen; Disulfide bonds: 2-5) -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 1 mg/ml -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
由来
Synthetic
-
研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (2)
ab120675 は 2 報の論文で使用されています。
- Hall EA et al. PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins. Am J Hum Genet 100:706-724 (2017). PubMed: 28413018
- Bull FA et al. Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by ß-arrestin2 and c-Src. Sci Rep 7:9969 (2017). PubMed: 28855588