製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to DPAGT1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, from a region within N terminal amino acids 27-57 of Human DPAGT1 (NP_001373.2).

  • ポジティブ・コントロール
    • ZR-75-1 cell lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab116667 was purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG

アプリケーション

Our Abpromise guarantee covers the use of ab116667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 46 kDa.

ターゲット情報

  • 機能
    Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.
  • パスウェイ
    Protein modification; protein glycosylation.
  • 関連疾患
    Defects in DPAGT1 are the cause of congenital disorder of glycosylation type 1J (CDG1J) [MIM:608093]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • 配列類似性
    Belongs to the glycosyltransferase 4 family.
  • 細胞内局在
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ALG7 antibody
    • AU021132 antibody
    • CDG Ij antibody
    • CDG1J antibody
    • CMS13 antibody
    • CMSTA2 antibody
    • D11S366 antibody
    • DGPT antibody
    • Dolichyl phosphate (UDP N acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc 1 P transferase) antibody
    • Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 antibody
    • DPAGT1 antibody
    • DPAGT2 antibody
    • G1PT antibody
    • GlcNAc 1 P transferase 1 antibody
    • GlcNAc-1-P transferase antibody
    • Gnpta antibody
    • GPT antibody
    • GPT_HUMAN antibody
    • H2afx antibody
    • N-acetylglucosamine-1-phosphate transferase antibody
    • UAGT antibody
    • UDP GlcNAc:dolichyl phosphate N acetylglucosaminephosphotransferase antibody
    • UDP N acetylglucosamine dolichyl phosphate N acetylglucosaminephosphotransferase 1 antibody
    • UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase antibody
    • UGAT antibody
    see all

画像

  • Anti-DPAGT1 antibody (ab116667) at 1/100 dilution + ZR-75-1 cell lysate at 35 µg

    Predicted band size : 46 kDa

プロトコール

参考文献

ab116667 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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