Anti-DP1 抗体 [SPM178], prediluted (ab53924)

製品の概要

  • 製品名Anti-DP1 antibody [SPM178], prediluted
    DP1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [SPM178] to DP1, prediluted
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Recombinant DP1 protein.

  • エピトープAmino acids 83-204.
  • ポジティブ・コントロール
    • MAD109 or Raji cells. Human tonsil.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: Ready to use for 30 min at room temperature.
    Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
    • 組織特異性Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.
    • 配列類似性Belongs to the E2F/DP family.
    • 翻訳後修飾Phosphorylation by E2F-1-bound cyclin A-CDK2, in the S phase, inhibits E2F-mediated DNA binding and transactivation.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DP 1 antibody
      • DP1 antibody
      • DRTF1 antibody
      • DRTF1-polypeptide 1 antibody
      • E2F dimerization partner 1 antibody
      • E2F related transcription factor antibody
      • TFDP1 antibody
      • TFDP1_HUMAN antibody
      • Transcription factor Dp-1 antibody
      • Transcription factor sequence-specific, DRTF1 antibody
      see all

    Anti-DP1 antibody [SPM178], prediluted 画像

    • ab53924 (prediluted) staining DP1 in formalin fixed, paraffin embedded human tonsil tissue by Immunohistochemistry.

    Anti-DP1 antibody [SPM178], prediluted (ab53924) 使用論文

    ab53924 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"