製品の概要

  • 製品名
    Doxorubicin hydrochloride
  • 製品の詳細
    Topoisomerase II inhibitor. Antibiotic with cytotoxic actions.
  • 別名
    • Adriamycin
  • 生理活性の詳細

    Topoisomerase II inhibitor (IC50 = 100 nM, Hep3B cells). DNA intercalator that prevents synthesis of nucleic acid. Induces apoptosis.

  • 精製度
    > 98%

製品の特性

参考文献

This product has been referenced in:
  • Sauter KA  et al. Doxorubicin and daunorubicin induce processing and release of interleukin-1ß through activation of the NLRP3 inflammasome. Cancer Biol Ther 11:1008-16 (2011). Read more (PubMed: 21464611) »
  • Lal S  et al. Pharmacogenetics of target genes across doxorubicin disposition pathway: a review. Curr Drug Metab 11:115-28 (2010). Read more (PubMed: 20302569) »
  • Gieseler F  et al. Cytotoxicity of anthracyclines: correlation with cellular uptake, intracellular distribution and DNA binding. Ann Hematol 69 Suppl 1:S13-7 (1994). Read more (PubMed: 8061108) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab120629.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

登録