Anti-Dopamine Receptor D5 抗体, prediluted (ab32621)
製品の概要
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製品名Anti-Dopamine Receptor D5 antibody, prediluted
Dopamine Receptor D5 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to Dopamine Receptor D5, prediluted
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由来種Rabbit
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アプリケーション適用あり: IHC-Pmore details
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種交差性交差種: Human
交差が予測される動物種: Chicken
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免疫原
Synthetic peptide:
CEGEISLDKI TPFTPNGFH
, corresponding to C terminal amino acids 459-477 of Human Dopamine Receptor D5. -
ポジティブ･コントロール
- Human brain tissue.
製品の特性
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製品の状態Prediluted
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保存方法Shipped at 4°C. Store at +4°C.
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バッファーPreservative: 0.1% Sodium Azide
Constituents: 1% BSA, 50mM Tris, pH 7.6 -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab32621 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
追加情報
IHC-P: Use Neat for 30 min at room temperature. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
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組織特異性Neuron-specific, localized primarily within limbic regions of the brain.
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関連疾患Defects in DRD5 are a cause of benign essential blepharospasm (BEB) [MIM:606798]. BEB is a primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness.
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配列類似性Belongs to the G-protein coupled receptor 1 family.
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細胞内局在Cell membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 1816 Human
- Omim: 126453 Human
- SwissProt: P21918 Human
- Unigene: 380681 Human
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別名
- D(1B) dopamine receptor antibody
- D(5) dopamine receptor antibody
- D1 beta dopamine receptor antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dopamine Receptor D5 antibody, prediluted (ab32621)Ab32621, prediluted, staining Dopamine Receptor D5 in formalin fixed paraffin embedded human brain tissue sections by Immunohistochemistry.
参考文献
ab32621 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"