製品の概要

  • 製品名Anti-Dopamine Receptor D5 antibody
    Dopamine Receptor D5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Dopamine Receptor D5
  • アプリケーション適用あり: IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chicken
  • 免疫原

    Synthetic peptide: CEGEISLDKI TPFTPNGFH, corresponding to C terminal amino acids 459-477 of Human Dopamine Receptor D5.

  • ポジティブ・コントロール
    • Human brain tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab32620 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
  • 組織特異性Neuron-specific, localized primarily within limbic regions of the brain.
  • 関連疾患Defects in DRD5 are a cause of benign essential blepharospasm (BEB) [MIM:606798]. BEB is a primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness.
  • 配列類似性Belongs to the G-protein coupled receptor 1 family.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • D(1B) dopamine receptor antibody
    • D(5) dopamine receptor antibody
    • D1 beta dopamine receptor antibody
    • D1B dopamine receptor antibody
    • D1beta dopamine receptor antibody
    • D5 dopamine receptor antibody
    • DBDR antibody
    • Dopamine D5 receptor antibody
    • Dopamine receptor D1B antibody
    • dopamine receptor D5 antibody
    • DRD 1B antibody
    • DRD 5 antibody
    • DRD1B antibody
    • DRD1L2 antibody
    • DRD5 antibody
    • DRD5_HUMAN antibody
    • MGC10601 antibody
    see all

Anti-Dopamine Receptor D5 antibody 画像

  • Ab32620, at a 1/50 dilution, staining Dopamine Receptor D5 in formalin fixed paraffin embedded human brain tissue by Immunohistochemistry.
  • ICC/IF image of ab32620 stained SKNSH cells. The cells were 4% formaldehyde (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab32620, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899 Dylight 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Dopamine Receptor D5 antibody (ab32620) 使用論文

ab32620 has not yet been referenced specifically in any publications.

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