製品の概要

  • 製品名Anti-Dopamine beta Hydroxylase antibody [8.F.304]
    Dopamine beta Hydroxylase 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [8.F.304] to Dopamine beta Hydroxylase
  • アプリケーション適用あり: ELISA, ICC, WB, RIDmore details
  • 種交差性
    交差種: Rat
    非交差種: Mouse, Rabbit, Guinea pig, Cat, Human
  • 免疫原

    Full length protein (Rat)

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab31126 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
ICC Use at an assay dependent dilution.
WB Use at an assay dependent dilution.
RID Use at an assay dependent dilution.

ターゲット情報

  • 機能Conversion of dopamine to noradrenaline.
  • パスウェイCatecholamine biosynthesis; (R)-noradrenaline biosynthesis; (R)-noradrenaline from dopamine: step 1/1.
  • 関連疾患Defects in DBH are the cause of dopamine beta-hydroxylase deficiency (DBH deficiency) [MIM:223360]; also known as norepinephrine deficiency or noradrenaline deficiency. This disorder is characterized by profound deficits in autonomic and cardiovascular function, but apparently only subtle signs, if any, of central nervous system dysfunction.
  • 配列類似性Belongs to the copper type II ascorbate-dependent monooxygenase family.
    Contains 1 DOMON domain.
  • 細胞内局在Cytoplasmic vesicle > secretory vesicle lumen. Cytoplasmic vesicle > secretory vesicle > chromaffin granule lumen and Cytoplasmic vesicle > secretory vesicle membrane. Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • dbh antibody
    • DBM antibody
    • Dopamine beta hydroxylase antibody
    • Dopamine beta monooxygenase antibody
    • Dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody
    • Dopamine beta-monooxygenase antibody
    • DOPO_HUMAN antibody
    • OTTHUMP00000022501 antibody
    • Soluble dopamine beta-hydroxylase antibody
    see all

Anti-Dopamine beta Hydroxylase antibody [8.F.304] (ab31126) 使用論文

This product has been referenced in:
  • Coll M  et al. Down-regulation of genes related to the adrenergic system may contribute to splanchnic vasodilation in rat portal hypertension. J Hepatol 49:43-51 (2008). WB ; Rat . Read more (PubMed: 18457899) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab31126.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"