製品の概要

  • 製品名Anti-DOK6 antibody
    DOK6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DOK6
  • アプリケーション適用あり: WB, ELISA, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide derived from an internal sequence within human DOK6.

  • ポジティブ・コントロール
    • COLO cell extracts. A549 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab72730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 38 kDa (predicted molecular weight: 38 kDa).
ELISA 1/10000.
ICC/IF 1/500 - 1/1000.

ターゲット情報

  • 関連性DOK6 (docking protein 6) is a novel member of the DOK4/5 subclass of the p62 DOK family of intracellular adaptor molecules. DOK6 is highly expressed in the developing central nervous system and is co expressed with Ret in several locations, including sympathetic, sensory, and parasympathetic ganglia, as well as in the ureteric buds of the developing kidneys. Pull down assays using the DOK6 phosphotyrosine binding (PTB) domain and GDNF activated Ret indicate that DOK6 binds to the phosphorylated Ret Tyr(1062) residue. Moreover, ligand activation of Ret resulted in phosphorylation of tyrosine residue(s) located within the unique C terminus of DOK6 predominantly through a Src dependent mechanism, indicating that DOK6 is a substrate of the Ret Src signaling pathway.
  • 参照データベース
  • 別名
    • Docking protein 5 antibody
    • Docking protein 5 like antibody
    • Docking protein 6 antibody
    • DOK 6 antibody
    • DOK5 antibody
    • DOK5L antibody
    • DOK6 antibody
    • Downstream of tyrosine kinase 6 antibody
    • HsT3226 antibody
    • MGC20785 antibody
    • Protein dok 5 antibody
    see all

Anti-DOK6 antibody 画像

  • All lanes : Anti-DOK6 antibody (ab72730) at 1/500 dilution

    Lane 1 : COLO cell extract
    Lane 2 : COLO cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 38 kDa
    Observed band size : 38 kDa
  • ab72730 at 1/500 dilution staining DOK6 in A549 cells by Immunofluorescence, in the absence or presence of the immunising peptide.

Anti-DOK6 antibody (ab72730) 使用論文

ab72730 has not yet been referenced specifically in any publications.

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