製品の概要

  • 製品名Anti-DOK6 antibody
    DOK6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DOK6
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 281-330 (

    IYSLQGHGFGSSKMSRAQTFPSYAPEQSEEAQQPLSRSSSYGFSYSSSLI

    ) of Human DOK6 (NP_689934).

  • ポジティブ・コントロール
    • COLO205 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab102621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性DOK6 (docking protein 6) is a novel member of the DOK4/5 subclass of the p62 DOK family of intracellular adaptor molecules. DOK6 is highly expressed in the developing central nervous system and is co expressed with Ret in several locations, including sympathetic, sensory, and parasympathetic ganglia, as well as in the ureteric buds of the developing kidneys. Pull down assays using the DOK6 phosphotyrosine binding (PTB) domain and GDNF activated Ret indicate that DOK6 binds to the phosphorylated Ret Tyr(1062) residue. Moreover, ligand activation of Ret resulted in phosphorylation of tyrosine residue(s) located within the unique C terminus of DOK6 predominantly through a Src dependent mechanism, indicating that DOK6 is a substrate of the Ret Src signaling pathway.
  • 参照データベース
  • 別名
    • Docking protein 5 antibody
    • Docking protein 5 like antibody
    • Docking protein 6 antibody
    • DOK 6 antibody
    • DOK5 antibody
    • DOK5L antibody
    • DOK6 antibody
    • Downstream of tyrosine kinase 6 antibody
    • HsT3226 antibody
    • MGC20785 antibody
    • Protein dok 5 antibody
    see all

Anti-DOK6 antibody 画像

  • Anti-DOK6 antibody (ab102621) at 1 µg/ml + COLO205 cell lysate at 10 µg

    Predicted band size : 38 kDa

Anti-DOK6 antibody (ab102621) 使用論文

ab102621 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"