製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to DOK3
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 434 and 496 of Human DOK3 (NP_079148).

  • ポジティブ・コントロール
    • A431 whole cell lysate

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab97297 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 53 kDa.

ターゲット情報

  • 機能
    DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function.
  • 組織特異性
    Expressed in spleen.
  • 配列類似性
    Belongs to the DOK family. Type A subfamily.
    Contains 1 IRS-type PTB domain.
    Contains 1 PH domain.
  • ドメイン
    PTB domain mediates receptor interaction.
  • 翻訳後修飾
    Constitutively tyrosine-phosphorylated.
    On IL2 stimulation, phosphorylated on C-terminal tyrosine residues possibly by Src kinases. Can also be phosphorylated by ABL kinase.
  • 細胞内局在
    Cytoplasm. Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Docking protein 3 antibody
    • DOK 3 antibody
    • DOK Like Protein antibody
    • Dok3 antibody
    • DOK3_HUMAN antibody
    • DOKL Pending antibody
    • Downstream of tyrosine kinase 3 antibody
    • p62 DOK Like Protein antibody
    see all

Anti-DOK3 antibody 画像

  • Anti-DOK3 antibody (ab97297) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 53 kDa

プロトコール

Anti-DOK3 antibody (ab97297) 使用論文

ab97297 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab97297.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録