Anti-DOCK2 抗体 [EPR6647] (ab124838)

製品の概要

  • 製品名Anti-DOCK2 antibody [EPR6647]
    DOCK2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR6647] to DOCK2
  • アプリケーション適用あり: WB, IHC-Pmore details
    適用なし: Flow Cyt,ICC or IP
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to residues near the C-terminus of Human DOCK2 protein (Q92608).

  • ポジティブ・コントロール
    • Jurkat and Raji cell lysates and Human lung tissue.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab124838 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 212 kDa.
IHC-P 1/50 - 1/100. Antigen retrieval is not recommended.
  • 追加情報Is unsuitable for Flow Cyt,ICC or IP.
  • ターゲット情報

    • 関連性DOCK2 (dedicator of cytokinesis 2) is a hematopoietic cell-specific protein that participates in the cytoskeletal rearrangements required for lymphocyte migration in response to chemokines. DOCK2 activates the small GTPases RAC1 and RAC2 and may also be involved in IL2 transcriptional activation via the activation of RAC2.
    • 細胞内局在Intracytoplasmic membrane. Peripheral membrane protein. Note=Colocalizes with F-actin.
    • 参照データベース
    • 別名
      • Dedicator of cyto kinesis 2 antibody
      • Dedicator of cytokinesis 2 antibody
      • Dedicator of cytokinesis protein 2 antibody
      • DOCK 2 antibody
      • FLJ46592 antibody
      • KIAA0209 antibody
      see all

    Anti-DOCK2 antibody [EPR6647] 画像

    • All lanes : Anti-DOCK2 antibody [EPR6647] (ab124838) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : Raji cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 212 kDa
    • ab124838, at 1/50 - 1/100, staining DOCK2 in Human lung tissue by immunohistochemistry [Paraffin Embedded Tissues (IHC-P)].

    Anti-DOCK2 antibody [EPR6647] (ab124838) 使用論文

    ab124838 has not yet been referenced specifically in any publications.

    Product Wall

    You are correct, we observed better staining in IHC-P with ab124838 when no antigen retrieval was used. Thus, we recommend skipping the antigen retrieval step in your protocol. This may vary depending on your tissue type and processing methods, so it m...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"