製品の概要

  • 製品名Anti-DOCK1 antibody
    DOCK1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DOCK1
  • 特異性ab92710 detects endogenous levels of total DOCK1 protein.
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide derived from an internal region of Human DOCK1.

  • ポジティブ・コントロール
    • HeLa cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab92710 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報ELISA: 1/40000.
    WB: 1/500 - 1/1000. Predicted molecular weight: 215 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.
    • 組織特異性Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
    • 配列類似性Belongs to the DOCK family.
      Contains 1 DHR-1 (CZH-1) domain.
      Contains 1 DHR-2 (CZH-2) domain.
      Contains 1 SH3 domain.
    • ドメインThe DHR-2 domain is necessary and sufficient for the GEF activity.
    • 細胞内局在Cytoplasm. Membrane. Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-triphosphate.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 180 kDa protein downstream of CRK antibody
      • Ced5 antibody
      • Dedicator of Cytokinesis 1 antibody
      • Dedicator of cytokinesis protein 1 antibody
      • DOCK 1 antibody
      • DOCK 180 antibody
      • DOCK1 antibody
      • DOCK1_HUMAN antibody
      • DOCK180 antibody
      see all

    Anti-DOCK1 antibody 画像

    • All lanes : Anti-DOCK1 antibody (ab92710) at 1/500 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HeLa cell lysate with immunizing peptide at 10 µg

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 215 kDa

    Anti-DOCK1 antibody (ab92710) 使用論文

    ab92710 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab92710.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"