製品の概要

  • 製品名Anti-Dnmt3L antibody
    Dnmt3L 一次抗体 製品一覧
  • 製品の詳細
    Chicken polyclonal to Dnmt3L
  • 特異性ab28968 recognises Dnmt3L.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein corresponding to Human Dnmt3L.
    Database link: Q9UJW3

  • ポジティブ・コントロール
    • Purified recombinant Human Dnmt3L.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 特記事項(精製)ab28968 is a crude IgY preparation from egg yolks using a precipitation method (PEG, Polyethylene Glycol).
  • ポリ/モノポリクローナル
  • アイソタイプIgY
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab28968 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/5000. Detects a band of approximately 47 kDa (predicted molecular weight: 47 kDa).

ターゲット情報

  • 機能Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
  • 組織特異性Expressed at low levels in several tissues including testis, ovary, and thymus.
  • 配列類似性Belongs to the C5-methyltransferase family.
    Contains 1 ADD-type zinc finger.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cytosine 5 methyltransferase 3 like protein antibody
    • DNA (cytosine 5 ) methyltransferase 3 like antibody
    • DNA (cytosine-5)-methyltransferase 3-like antibody
    • DNA cytosine 5 methyltransferase 3 like protein antibody
    • DNA methyltransferase 3 like protein antibody
    • DNM3L_HUMAN antibody
    • Dnmt 3L antibody
    • Dnmt3l antibody
    • Human cytosine 5 methyltransferase 3 like protein antibody
    • MGC1090 antibody
    see all

Anti-Dnmt3L antibody 画像

  • Anti-Dnmt3L antibody (ab28968) at 1/500 dilution

    Predicted band size : 47 kDa
    Observed band size : 47 kDa

Anti-Dnmt3L antibody (ab28968) 使用論文

ab28968 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Cell lysate - nuclear (Hela cells)
Loading amount 40 µg
Specification Hela cells
Gel Running Conditions Reduced Denaturing (12%)
Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 20°C
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投稿 Sep 16 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"