製品の概要

  • 製品名Anti-Dnmt3L antibody
    Dnmt3L 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Dnmt3L
  • アプリケーション適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to Human Dnmt3L aa 322-337 conjugated to keyhole limpet haemocyanin.
    Sequence:

    RVWSNIPAIRSRHWAL


    Database link: Q9UJW3

  • ポジティブ・コントロール
    • Human tonsil tissue

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab115522 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1 - 1/1000.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
  • 組織特異性Expressed at low levels in several tissues including testis, ovary, and thymus.
  • 配列類似性Belongs to the C5-methyltransferase family.
    Contains 1 ADD-type zinc finger.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cytosine 5 methyltransferase 3 like protein antibody
    • DNA (cytosine 5 ) methyltransferase 3 like antibody
    • DNA (cytosine-5)-methyltransferase 3-like antibody
    • DNA cytosine 5 methyltransferase 3 like protein antibody
    • DNA methyltransferase 3 like protein antibody
    • DNM3L_HUMAN antibody
    • Dnmt 3L antibody
    • Dnmt3l antibody
    • Human cytosine 5 methyltransferase 3 like protein antibody
    • MGC1090 antibody
    see all

Anti-Dnmt3L antibody 画像

  • ab115522 at 10ug/ml staining Dnmt3L in Human tonsil tissue by immunohistochemistry (FFPE). Following primary incubation slides were incubated with biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Dnmt3L antibody (ab115522) 使用論文

ab115522 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"