製品の概要

  • 製品名Anti-DNER antibody
    DNER 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to DNER
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 368-477 of Human DNER

  • ポジティブ・コントロール
    • PC-12 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 90-100 kDa (predicted molecular weight: 78.4 kDa). Larger band size is due to glycosylation.

ターゲット情報

  • 機能Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.
  • 組織特異性Expressed in brain, spinal cord and adrenal gland.
  • 配列類似性Contains 10 EGF-like domains.
    Contains 1 follistatin-like domain.
  • 細胞内局在Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
  • Information by UniProt
  • 参照データベース
  • 別名
    • bet antibody
    • Brain EGF repeat-containing transmembrane protein antibody
    • Bret antibody
    • Delta and Notch-like epidermal growth factor-related receptor antibody
    • Delta notch like EGF repeat containing transmembrane antibody
    • Delta/notch like EGF repeat containing antibody
    • Delta/notch-like EGF-related receptor antibody
    • Dner antibody
    • DNER_HUMAN antibody
    • PRO299 antibody
    • Transmembrane protein Bet antibody
    • UNQ26 antibody
    see all

Anti-DNER antibody 画像



  • Predicted band size : 78.4 kDa

    Western Blot analysis of DNER antibody (ab57949).

Anti-DNER antibody (ab57949) 使用論文

ab57949 has not yet been referenced specifically in any publications.

Product Wall

Thank you for the inquiry. The calculated predicted molecular weight of DNER is indeed 78.4KDa but the protein is glycosylated, hence when testing on PC12 cell lysate a band at around 100kDa was detected. This band size has been reported in the lit...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"