製品の概要

製品の詳細

  • 由来Synthetic

特性

Our Abpromise guarantee covers the use of ab8373 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.1% BSA

関連情報

  • 別名
    • Acid DNase
    • Deoxyribonuclease 2
    • Deoxyribonuclease 2 alpha
    • Deoxyribonuclease II
    • Deoxyribonuclease II alpha
    • Deoxyribonuclease II lysosomal
    • Deoxyribonuclease-2-alpha
    • Deoxyribonuclease2
    • DeoxyribonucleaseII
    • DNASE 2
    • DNASE 2A
    • DNase II alpha
    • DNase II lysosomal
    • DNASE2
    • DNASE2A
    • DNaseII
    • DNL
    • DNL 2
    • DNL2
    • DNS2A_HUMAN
    • Lysosomal DNase II
    • R31240 2
    • R31240_2
    see all
  • 機能Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
  • 配列類似性Belongs to the DNase II family.
  • 翻訳後修飾Glycosylated. Mutations that eliminate N-glycosylation sites reduce activity, but enzymatic deglycosylation has no effect.
  • 細胞内局在Lysosome.
  • Information by UniProt

DNase II peptide (ab8373) 使用論文

ab8373 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"